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Structure of cell death protein BAX

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Structure of cell death protein BAX

Structural biology has revealed how the BAX protein is activated. The blue and yellow region shows where BH3-only proteins transiently bind BAX to release its 'tail' (red) that anchors BAX into mitochondrial membrane. This research helped to reveal how the transient ‘hit-and-run’ interaction between BAX and BH3-only proteins could be an ...

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